2024 - Sanzymebiologics

Bacillus coagulans for pet health

Maintaining the intestinal health of dogs and cats is becoming increasingly important as pet owners pay more attention to the health of their pets. The utilization of probiotics is an effective strategy to enhance the health of dogs and cats. The administration of probiotics can improve the balance of the intestinal microbiota, suppress inflammation, enhance immune function, and alleviate intestinal disorders in dogs and cats. The administration of probiotics to dogs has shown positive effects on the gut health and can alleviate some intestinal diseases and disorders in dogs, although the underlying mechanisms are largely unresolved.
The Gastro Intestinal Tract microbiota contributes to maintaining intestinal homeostasis via multifaceted mechanisms, such as defence against intestinal pathogens, facilitation of nutrient digestion and absorption, improvement in barrier function, stimulation of intestinal development, and modulation of the immune system. Bacterial metabolites, such as short-chain fatty acids (SCFAs), secondary bile acids, and tryptophan metabolites, are key mediators of host−microbiota interactions and play important roles in influencing host health. SCFAs are products of bacterial fermentation of dietary fibres, mainly including acetate, propionate, and butyrate, which contribute to intestinal and host health by serving as energy substrates for colonic epithelial cells, maintenance of epithelial barrier integrity, regulation of energy metabolism, and anti-inflammatory effects
The utilization of probiotics in dogs and cats has been shown to improve the gut microbiota balance, modulate inflammation, enhance immune function, and protect against infections caused by enteropathogens. Probiotics also exert immunomodulatory activities in dogs. Feeding of Bacillus coagulans elevated faecal IgA and plasma IgG levels in dogs.
Moreover, studies have suggested improved faecal quality and reduced nitrogen fermentation through probiotic treatments in dogs
Feeding of probiotics decreased the faecal pH and concentrations of total biogenic amines and ammonia. Dietary supplementation with Bacillus subtilis and Bacillus licheniformis improved the faecal score, reduced nitrogen fermentation products in faeces, and reduced faecal odor in dogs. Dietary supplementation with Weissella cibaria JW15 decreased fecal ammonia emission in dogs.

Probiotics play a crucial role in promoting digestive health in dogs. Following are the benefits of probiotics feeding to dogs.

It will improve gut bacteria balance: Probiotics introduce beneficial bacteria, crowds out pathogens, and maintains a healthy gut microbiome.
Probiotics will enhance nutrient absorption: Probiotics increase nutrient uptake, reducing waste and minimizing faecal volume.
It will reduce diarrhoea and loose stool: Probiotics regulate water absorption, improving stool consistency.
It will increase immune system function: Probiotics stimulate immune cells, boosting defence against infections.
It will reduce inflammation: Probiotics produce anti-inflammatory compounds, soothing gut irritation.
It will improve digestive enzyme production: Probiotics enhance enzyme secretion, facilitating nutrient breakdown.

Key Probiotic Strains for Dogs

Bacillus coagulans
Lactobacillus acidophilus
Bifidobacterium bifidum
Streptococcus thermophilus
Enterococcus faecium

Following Health Conditions can be improved by Probiotics feeding to Dogs

Diarrhea
Constipation
Gastrointestinal upset
Inflammatory bowel disease (IBD)
Food sensitivities
Allergies

The Role of Bacillus Coagulans

Bacillus coagulans is used as feed additive in pet food, including dog food, to support gut health.
Following are the beneficial effects of Bacillus coagulans feeding:

Improved faecal consistency: Bacillus coagulans helps regulate water absorption, reducing diarrhea or loose stool.
Reduced faecal odor: By promoting beneficial gut bacteria, Bacillus coagulans minimizes the production of volatile organic compounds (VOCs) responsible for unpleasant odours.
Increased faecal solidity: Bacillus coagulans enhances nutrient absorption, leading to more solid, well-formed stools.
Enhanced nutrient utilization: By improving gut health, Bacillus coagulans optimizes nutrient absorption, reducing waste and minimizing fecal volume.

Optimal dosage:

The ideal dosage of Bacillus coagulans for dogs varies depending on factors like age, size, and health status. Typical dosages range from 1-10 billion CFU (Colony-Forming Units) per kilogram of body weight per day.

Advantages of adding Bacillus coagulans as a probiotic strain in various formats compared to other probiotic strains

Stability: Bacillus coagulans is known for its exceptional stability under various conditions, including heat and acidity. This makes it ideal for inclusion in a wide range of products, such as dry kibble, canned foods, dog treats, biscuits and many other formats without losing efficacy.
Shelf Life: Its spore-forming nature allows Bacillus coagulans to remain viable for longer periods, enhancing the shelf life of pet food products compared to many other probiotics that may have shorter shelf lives.
Ease of Formulation: Bacillus coagulans can be easily incorporated into different formats, including powders, pellets, and liquid forms, providing flexibility for manufacturers when developing pet food and supplements.
Rapid Colonization: This strain can quickly colonize the gut, offering faster benefits in digestive health and overall well-being compared to some other probiotics that may take longer to establish.
Versatile Health Benefits: Bacillus coagulans not only supports digestive health but also offers immune system support and anti-inflammatory properties, making it a multifunctional choice for pet formulations.
Cost-Effectiveness: Bacillus coagulans offers a cost-effective solution for manufacturers due to its robustness and longevity. This strain requires fewer resources for storage and handling compared to more sensitive probiotic strains, which can be challenging to maintain. Additionally, the overages needed to meet target label claims for Bacillus coagulans are typically lower, further enhancing its economic appeal. By reducing both storage costs and the quantity needed to achieve effective dosing, manufacturers can optimize their production processes while delivering high-quality probiotic products.
Palletability: Bacillus coagulans probiotics has no impact on the taste and flavor of the final product format making it ideal for the inclusion in various pet foods
Proven Efficacy: Extensive research and clinical studies have demonstrated the benefits of Bacillus coagulans in improving gut health and reducing gastrointestinal issues in pets, giving manufacturers confidence in its effectiveness.

By choosing Bacillus coagulans over other probiotic strains, manufacturers can create more resilient and effective pet food formulations that meet the health needs of pets while ensuring product longevity and consumer satisfaction.

About Sanzyme Biologics

Sanzyme Biologics is a pioneer in the field of probiotics, boasting over 50 years of expertise in probiotic manufacturing. The company specializes in producing high-quality probiotic strains, supported by extensive research and clinical studies that promote these strains for human, animal, and companion animal health. As a leading manufacturer, Sanzyme Biologics supplies its probiotic strains to over 40 countries, making a significant impact on the global probiotics market. Sanzyme Biologics offers clinically studied Bacillus coagulans for dogs and cats, promoting digestive health, and clinically studied Bacillus clausii for oral and immune health. With a commitment to quality and research-driven solutions, Sanzyme Biologics continues to set the standard in the industry.

Reference Studies:

A study published in the Journal of Animal Science found that Bacillus coagulans supplementation reduced faecal moisture content and improved stool quality in dogs.
Research in the Journal of Veterinary Internal Medicine showed that Bacillus coagulans improved gut health and reduced diarrhoea in dogs with gastrointestinal issues.
American Animal Hospital Association (AAHA) recommends probiotics for gastrointestinal health.
Journal of Animal Science study: Probiotics reduce diarrhea in puppies.
Veterinary Microbiology study: Probiotics enhance gut health in dogs with IBD.

Probiotics for Beverage Applications

In recent years, probiotics have moved from niche supplements to mainstream wellness products.
Among the probiotic strains available, Bacillus coagulans has emerged as a noteworthy contender,
particularly in the realm of beverages. This robust bacterium, known for its remarkable stability and
health benefits, is increasingly being incorporated into various drink formats. This blog delves into
why Bacillus coagulans is making waves in the beverage industry, its benefits, applications, and the
future it holds.

Understanding Bacillus coagulans

Bacillus coagulans is a type of probiotic bacteria that belongs to the genus Bacillus. Unlike many
probiotics that exist in a vegetative state, Bacillus coagulans forms spores, which are highly resilient
to environmental stresses such as heat, and acidity This spore-forming ability gives Bacillus
coagulans a significant advantage in various applications, including beverages where stability and
viability are critical.

Unique Characteristics

Spore Formation: Bacillus coagulans forms spores that can survive harsh conditions, making
it particularly well-suited for inclusion in beverages that may be exposed to high
temperatures or acidic environments.

Stability: Due to its spore-forming nature, Bacillus coagulans is less affected by changes in
pH and temperature compared to non-spore-forming probiotics. This stability allows it to
maintain its effectiveness throughout the product’s shelf life

Survivability: The spores are designed to withstand the acidic environment of the stomach
and germinate in the intestines, where they can exert their beneficial effects on gut health.

Probiotic applications in Beverages

The versatility of Bacillus coagulans makes it suitable for a wide range of beverage applications. Let’s
explore how this probiotic can be effectively incorporated into various drink formats.

1. Probiotic Soda

The market for low calorie and sparkling drinks are growing faster, probiotic Soda is gaining
popularity as a convenient and refreshing way to consume probiotics. Bacillus coagulans is an ideal
for probiotic soda due to its:

Stability in Carbonated Environments: Bacillus coagulans forms spores that are resistant to
heat and acidity, making it well-suited for carbonated beverages.

Viability in Acidic Conditions: The strain can survive the acidic environment of both the soda
and the stomach, ensuring that beneficial bacteria reach the intestines.

2. Smoothies and Juices

Smoothies and juices are a popular choice for health-conscious consumers looking to boost their
nutrition. Adding Bacillus coagulans to smoothies and juices offers:

Flexible Dosage: Probiotic powders can be easily blended into smoothies and juices,
allowing for customizable dosages based on individual needs and preferences.

Enhanced Nutritional Profile: Incorporating Bacillus coagulans can enhance the health
benefits of smoothies and juices, making them a more comprehensive source of nutrients
and probiotics.

3. Fermented Drinks

Fermented beverages like kombucha, kefir, and other probiotic-rich drinks are already known for
their beneficial bacteria. Adding Bacillus coagulans in kombucha and other fermented beverage:

Diversify Probiotic Strains: Including Bacillus coagulans alongside existing probiotic strains
can offer a broader range of health benefits and support a more diverse gut microbiota.

Improve Product Efficacy: The combination of different probiotics can enhance the overall
effectiveness of the beverage in promoting digestive health.

4. Functional Beverages
Functional beverages, including energy drinks, wellness shots, and sports drinks, are increasingly
incorporating probiotics to offer added health benefits. Bacillus coagulans can be integrated into
these products to:

Support Gut Health: Adding probiotics to functional beverages can provide digestive and
immune support alongside the primary benefits of the drink, such as increased energy or
enhanced hydration.

Appeal to Health-Conscious Consumers: Probiotic-enriched functional beverages cater to
consumers who are looking for multi-benefit products that support both their health and
wellness goals.

Formulation Considerations
When incorporating Bacillus coagulans into beverages, several key considerations must be taken into
account to ensure product efficacy and consumer satisfaction.

1. pH Levels
The pH of a beverage can affect probiotic viability. While Bacillus coagulans is more resilient to pH
changes compared to many other probiotics, it is still important to:

Optimize pH Levels: Ensure that the pH of the beverage is within a range that supports the
stability and activity of Bacillus coagulans.

Monitor Stability: Conduct stability testing to confirm that the probiotic remains viable
throughout the product’s shelf life.

2. Temperature and Processing
Processing conditions, including heat and pressure, can impact the viability of probiotics. Bacillus
coagulans is known for its heat resistance, but:

Control Processing Conditions: Manage processing temperatures and other conditions to
minimize any potential impact on the probiotic content.

3. Dosage

Determining the appropriate dosage of Bacillus coagulans is essential for delivering meaningful
health benefits. Consider:

Research-Based Dosage: Use research and guidelines to establish the effective dosage range
for Bacillus coagulans in beverages.

Labeling and Claims: Ensure that dosage levels are accurately reflected on product labels
and align with any health claims made.

Consumer Trends and Market Potential

1. Growing Interest in Functional Beverages

The functional beverage market is expanding as consumers seek products that offer added health
benefits. Bacillus coagulans fits perfectly into this trend by providing:

Digestive and Immune Support: Probiotic beverages cater to consumers looking for
functional products that support gut health and overall wellness.

Convenient Health Solutions: Beverages with Bacillus coagulans offer a convenient and
enjoyable way to incorporate probiotics into daily routines.

2. Health-Conscious Consumers
Today’s consumers are increasingly aware of the impact of diet on health. Probiotic beverages,
particularly those featuring Bacillus coagulans, appeal to:

Consumers Seeking Wellness: Health-conscious individuals are looking for products that
support their wellness goals, making probiotic beverages a popular choice.

Families and Children: Probiotic drinks can be a family-friendly option, providing health
benefits in a format that is easy for both adults and children to consume.

3. Innovation Opportunities

Bacillus coagulans opens up numerous possibilities for innovation in beverage formulation. Potential
opportunities include:

New Product Developments: Explore new beverage concepts and formats that incorporate
Bacillus coagulans, such as probiotic-infused iced teas or functional energy drinks.

Flavor and Functionality: Experiment with different flavors and functional benefits to create
unique probiotic beverages that stand out in the market.

About Bacillus coagulans SNZ 1969®

Bacillus coagulans SNZ 1969®, isolated from Green Malt, boasts a distinguished history of over 50
years of successful use across various age groups. Supported by more than 30 human clinical studies,
promoting gut health, oral health, and women's health. Resilient and versatile, it presents an
exciting prospect for integration into various food applications. It holds several certifications,
including USFDA GRAS (Adult & Infant), Health Canada approval, claims notified at FSANZ, QPS in the
EU, and is permitted by FSSAI.

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Understanding CFU in Probiotics: What You Need to Know

Probiotics have gained a lot of popularity in recent years, with many people turning to them to improve their gut health. Probiotics are live microorganisms that can be found in certain foods and supplements. They are believed to help restore the natural balance of bacteria in your gut, which can have a positive effect on your overall health.

When it comes to choosing a probiotic supplement, you may have come across the term CFU. CFU stands for Colony Forming Units, and it is a measure of the number of viable microorganisms in a probiotic product. In this blog post, we will dive into what CFU means and why it is important when choosing a probiotic supplement.

What are CFUs?

CFUs are a measure of the number of viable microorganisms in a probiotic product. Viable microorganisms are those that are alive and able to reproduce. CFUs are typically measured per gram or per serving of the probiotic product. The higher the CFU count, the more microorganisms are present in the product.

Why are CFUs important in probiotics?

CFUs are important in probiotics because they help to ensure that the product contains a sufficient number of viable microorganisms to provide the intended health benefits. Probiotics are meant to introduce beneficial bacteria into your gut, and the CFU count helps to ensure that there are enough of these bacteria to make a difference.

It is important to note that the number of CFUs needed for a probiotic to be effective can vary depending on the strain of bacteria used and the health condition being targeted. For example, a probiotic that is intended to help with diarrhea may require a higher CFU count than one that is intended to support overall gut health.

How to choose a probiotic based on CFUs

When choosing a probiotic supplement, the CFU count is just one of many factors to consider. It is also important to consider the strain(s) of bacteria used in the product, as well as any other ingredients and potential allergens.

In conclusion, CFUs are an important factor to consider when choosing a probiotic supplement. A higher CFU count can indicate that a product contains more viable microorganisms, which can increase the likelihood of it providing health benefits. However, it is important to consider other factors as well, such as the strain(s) of bacteria used, when choosing a probiotic supplement.

Why is there CFU difference between different probiotic strains?

CFU counts can vary for vegetative and spore-forming probiotics due to their different characteristics and survival rates.

Vegetative probiotics are live microorganisms that are in their active state and able to reproduce. They are more fragile and can be sensitive to environmental factors such as temperature, moisture, and acidity. Vegetative probiotics have a shorter shelf life and may require refrigeration to maintain their potency. As a result, vegetative probiotics may have higher CFU counts, typically ranging from 2-10 billion CFUs per serving.

On the other hand, spore-forming probiotics are microorganisms that can form a protective spore when conditions become unfavourable, allowing them to survive in harsh environments. Spore-forming probiotics have a longer shelf life and can withstand heat, acidity, and other adverse conditions. This makes them more stable and better suited for use in food products or supplements that do not require refrigeration. Spore-forming probiotics may have lower CFU counts, typically ranging from 150 million to 2 billion CFUs per serving.

It is important to note that CFU counts alone should not be the only factor to consider when choosing a probiotic supplement. The strain(s) of bacteria used and the health condition being targeted should also be taken into account. A probiotic supplement that contains a high CFU count but the wrong strain(s) may not be effective for the intended purpose. It is always best to consult with a healthcare professional before starting any new supplement regimen.

Bacillus coagulans SNZ 1969® is a spore-forming probiotic that requires lower CFU counts to be effective compared to vegetative strains. This is due to its unique ability to form heat-resistant spores, which protect the bacteria through digestion and ensure they reach the intestines alive. Unlike vegetative strains, which are more fragile and need higher CFU counts to survive harsh conditions, Bacillus coagulans’ spores are more resilient, making lower CFU concentrations still effective. This resilience not only simplifies storage and handling but also enhances its stability and effectiveness in promoting gut health and supporting a balanced microbiome.

Probiotics for Aquaculture

Introduction

In recent years, the aquaculture industry has seen significant advancements in improving the health and productivity of aquatic organisms. One promising development is the use of probiotics – beneficial microorganisms that promote a balanced gut microbiome in fish and other aquatic species. This article explores the benefits and applications of probiotics in aquaculture, focusing on their role in enhancing immune function, nutrient absorption, and overall sustainability.

The Role of Probiotics in Aquaculture:

Probiotics are live microorganisms that, when administered in adequate amounts, confer health benefits on the host. In aquaculture, these beneficial bacteria, yeast, and other organisms play a crucial role in several key areas:

Enhanced Immune Function:

Probiotics help strengthen the immune system of aquatic species, making them more resilient to pathogens and diseases. By maintaining a healthy gut microbiota, probiotics reduce the incidence of infections and improve overall survival rates in aquaculture farms.

Improved Nutrient Utilization:

Efficient nutrient absorption is essential for the growth and development of fish and shrimp. Probiotics aid in breaking down complex nutrients, such as proteins and carbohydrates, into simpler forms that are more easily absorbed by aquatic organisms. This leads to better feed conversion ratios and optimized growth rates.

Water Quality Management:

Aquaculture systems often face challenges related to water quality, including the accumulation of organic waste and harmful metabolites. Probiotics help maintain water quality by enhancing the breakdown of organic matter and reducing ammonia and nitrite levels, creating a healthier environment for aquatic species.

Sustainable Aquaculture Practices:

As consumers and regulatory bodies place greater emphasis on sustainable food production, probiotics offer a natural and environmentally friendly solution. By reducing the need for antibiotics and chemical treatments, probiotics contribute to a more sustainable aquaculture industry.

Types of Probiotics Used in Aquaculture:

There are various types of probiotics used in aquaculture, including:

Lactic Acid Bacteria (LAB): Known for their ability to inhibit pathogenic bacteria and improve digestion. Lactic acid bacteria, notably Lactobacillus sp., Bifidobacterium sp. and Streptococcus sp. are effective against diseases caused by Vibrio sp. (Gatesoupe,1994; Olsson et al., 1998).

Bacillus spp.: Effective in breaking down organic matter and enhancing nutrient absorption. Bacillus subtilis BT23 has inhibitory effects against vibriosis in tiger shrimp Penaeus monodon (Vaseeharan and Ramasamy 2003)

Yeast: Supports immune function and aids in the digestion of complex carbohydrates.

Choosing the right probiotic strain depends on factors such as the species of fish or shrimp, environmental conditions, and specific health challenges within the aquaculture system.

Application Methods:

Probiotics can be administered to aquatic organisms through several methods:

Direct Addition to Feed:

Probiotics for aquaculture can be incorporated into feed pellets or added as a powder or liquid during feeding.

Water Treatment:

Probiotics for aquaculture can be introduced directly into the aquaculture system to improve water quality and support the overall health of aquatic species.

Biofloc Systems:

In biofloc-based aquaculture systems, probiotics play a critical role in maintaining microbial balance and optimizing nutrient cycling.

Conclusion:

In conclusion, the use of probiotics in aquaculture represents a promising strategy for enhancing the health, growth, and sustainability of aquatic organisms. By improving immune function, nutrient utilization, and water quality management, probiotics contribute to more efficient and environmentally friendly aquaculture practices. As research continues to expand, the potential applications of probiotics in aquaculture are likely to grow, offering new opportunities for innovation and improvement in the industry.

By integrating probiotics into aquaculture operations, farmers can achieve better yields, reduce environmental impact, and meet the growing demand for sustainable seafood production.

Sanzyme Biologics one of the leading manufacturer and supplier of probiotics for aquaculture. Sanzyme Biologics manufactures proprietary probiotic strains, probiotic blends, enzymes and nutritional ingredients for humans, pets and farm animals in its state-of-the-art manufacturing facility in Hyderabad, India with over fermentation capacity of 350,000 L (one of the highest in the world). Sanzyme Biologics is certified FAMI-QS, NON-GMO, NSF, HALAL, KOSHER & ISO Producing a wide range of spore forming, shelf and process stable probiotic strains. In Animal Health -Sanzyme Biologics exports AMR Gene Free Probiotic strains of Bacillus subtilis (SAN 144BS), Bacillus coagulans (SAN 135BC), Bacillus licheniformis (SAN 136BL) & Saccharomyces boulardii (SAN 158SB).

Interested in incorporating probiotics into your aquaculture operation? Contact us today to learn more about our probiotic solutions and how they can benefit your farm

Probiotics for Poultry: Stress and Diarrhoea management

In the dynamic world of poultry farming, maintaining optimal health is paramount to ensure productivity and profitability. However, challenges such as stress and gastrointestinal issues like diarrhoea can disrupt poultry well-being, impacting both bird performance and farm economics. Fortunately, the integration of probiotics offers a promising solution for addressing these concerns effectively. In this comprehensive guide, we delve into the role of Probiotics in alleviating stress and managing diarrhoea in poultry, exploring their mechanisms of action and highlighting their significance for sustainable poultry production.

Understanding Probiotics: Probiotics, often hailed as “good bacteria,” are live microorganisms that confer health benefits when consumed in adequate amounts. In poultry farming, Probiotics primarily comprise beneficial bacterial strains like Lactobacillus, Bifidobacterium and Bacillus species. These Probiotic bacteria play a pivotal role in promoting gut health, modulating immune function, and supporting overall well-being in poultry.

Stress and Its Impact on Poultry Health:

Stress is an unavoidable aspect of intensive poultry production arising from factors such as housing, environmental fluctuations, production & reproduction, infections, transportation and management practices. When poultry experience stress, it results in immunological or metabolic consequences such as:

Regression of immune protective organs
Reduction of the oxidative metabolic capacity of mitochondria
Deficit of antioxidant reserves
Changes in the activity of antioxidant enzymes
Disruption of the gut mocrobiota

All these have a high adverse effect on the poultry bird leading to immune suppression, high susceptibility to infectious pathogens, loose droppings / diarrhoea, high FCR, decreased body weight, decreases egg production, soiled eggs, infertility / low egg hatchability and finally low ROI.

Physiological stress in particular to laying hens & breeder females is a major cause of concern, when they are turning from pre-lay to peak-lay. Physiological stress during this stage is due to rapidly developing ovaries & fallopian tubes along with an Estrogen surge. This increases nutritional requirement causing a burden on the digestive system. Because the Gut-Brain Axis takes a beating, immunity is hampered, pathogenic invasion & proliferation is rampant causing imbalance of intestinal flora which manifests to diarrhoea / loose droppings, vent pasting and soiled eggs.

Role of Probiotics in Stress Alleviation for poultry:

Probiotics offer a multifaceted approach to mitigating the negative effects of stress on poultry health. Through various mechanisms, Probiotics help modulate the stress response and enhance resilience in birds. Probiotic strains have been shown to downregulate the production of stress hormones and promoting a calmer physiological state in poultry. Additionally, Probiotics bolster gut health by strengthening the intestinal barrier and regulating immune function, thereby supporting birds in coping with stressors more effectively.

Managing Diarrhoea in Poultry:

Diarrhoea is a prevalent gastrointestinal ailment in poultry, characterized by loose or watery faeces and associated symptoms like dehydration and reduced feed intake. The causes of diarrhoea in poultry are diverse, ranging from infectious agents to dietary factors and stress. Regardless of the underlying cause, diarrhoea poses significant challenges to poultry health and farm profitability.

The Role of Probiotics in Diarrhoea Management:

Probiotics play a crucial role in managing diarrhoea in poultry by promoting gastrointestinal health and combating pathogenic bacteria. Unlike conventional antibiotics, which indiscriminately kill both harmful and beneficial bacteria, further impairing gut microbiota thereby hampering immunity and production. Probiotics target pathogens while preserving & nurturing the beneficial microflora in the gut. Probiotic bacteria outcompete pathogenic organisms for resources and adhesion sites in the intestinal mucosa, thereby reducing their colonization and proliferation. Moreover, Probiotic strains produce antimicrobial compounds like bacteriocins which inhibit the growth of pathogens contributing to diarrhoea resolution and prevention.

Choosing the Right Probiotic Strains

Selecting the appropriate Probiotic strains is paramount for achieving desired outcomes in poultry production. When choosing Probiotics for stress alleviation and diarrhoea management, factors such as strain specificity, viability, and compatibility with existing management practices must be considered. It’s essential to opt for Probiotic strains that have been scientifically validated for their efficacy in poultry health. Consulting with poultry health experts, nutritionists and veterinarians can aid in selecting the most suitable Probiotic strains for addressing specific health challenges in poultry flocks.

Applications of Probiotics in Poultry Farming:

Probiotics can be conveniently administered to poultry through various routes including feed and water. Incorporating probiotics into feed formulations is a common and effective method of delivery, ensuring consistent dosing and maximum efficacy. Probiotic supplements can also be added to drinking water. Regardless of the administration route, adherence to recommended dosage guidelines and proper storage practices is essential to maintain Probiotic viability and efficacy.

Sporich ResQ is a Probiotic formulation developed by SANZYME BIOLOGICS aimed at addressing poultry diarrhoea due to pathogens, stress, physiological or of unknown etiology. Sporich ResQ contains beneficial microorganisms – Bacillus coagulans (SAN 135BC) and Saccharomyces boulardii (SAN 158SB), which play a vital role in maintaining the balance of gut microbiota in poultry. Both Bacillus coagulans (SAN 135BC) and Saccharomyces boulardii (SAN 158SB) have been documented to specifically act in:

Stimulating the immune system
Synthesising different antimicrobial bacteriocins to inhibit pathogens
Producing enzyme metabolites to improve nutrient digestion and absorption
Modulating and colonizing the gut with beneficial microbes

Thus promoting a healthy gut environment, reducing stress and improving production parameters.

Sporich ResQ acts by:

Restoration of Gut Microflora Balance: Diarrhoea often occurs due to disruptions in the gut microbiota, such as the overgrowth of pathogenic bacteria. Sporich ResQ helps restore the balance of gut microflora by promoting the growth of beneficial bacteria, such as Lactobacillus and Bifidobacterium, which can outcompete harmful bacteria by reducing microbial count of Clostridium perfringens in both jejunum and ileum, thus controlling associated diarrhoea.
Reduction of Antibiotic Usage: In many cases, antibiotics have been traditionally used to manage diarrhoea in poultry. However, overuse of antibiotics can lead to the development of Antibiotic-Resistant Bacteria which pose risks to human health. Sporich ResQ offers a natural alternative to antibiotics, reducing the reliance on antimicrobial agents in poultry farming.
Enhanced Nutrient Absorption: Diarrhoea can lead to malabsorption of nutrients in poultry, resulting in poor growth and performance. Sporich ResQ restores Villi Height & Crypt Depth, thus facilitating better nutrient absorption, allowing poultry birds to utilize feed more efficiently and support optimal growth.
Improved Flock Health and Performance: Ultimately, the use of Sporich ResQ leads to improved overall flock health and performance. By reducing the incidence and severity of diarrhoea, poultry farmers can expect healthier birds, good & clean eggs, better growth rates, FCR’s and overall profitability.
Reducing the Risk of AMR: Both Bacillus coagulans (SAN 135BC) and Saccharomyces boulardii (SAN 158SB) – the Probiotic strains in Sporich ResQ have been tested for AMR Genes and have been documented as AMR Gene Negative. This goes a long way in Sporich ResQ being a potential candidate for reducing the risk of AMR which is posing a serious threat to humanity.

About SANZYME BIOLOGICS: A pioneer in fermentation technology with over 50 years of legacy in the area of Probiotics, SANZYME BIOLOGICS was founded as Uni-Sankyo in the year 1969 – a joint venture with Diachi Sankyo of Japan. SANZYME BIOLOGICS was the first company to manufacture and sell Probiotics & Enzymes in India and is today a market leader with presence in over 40 countries across the globe.

SANZYME BIOLOGICS manufactures proprietary Probiotic strains, Probiotic blends, enzymes and nutritional ingredients for humans, pets and farm animals in its state-of-the-art manufacturing facility in Hyderabad, India with fermentation capacity of over 350,000 L (one of the highest in the world).

SANZYME BIOLOGICS is certified FAMI-QS, NON-GMO, NSF, HALAL, KOSHER & ISO, producing a wide range of spore forming, shelf and process stable Probiotic strains. In Animal Health SANZYME BIOLOGICS exports AMR Gene Free Probiotic strains of Bacillus subtilis (SAN 144BS), Bacillus coagulans (SAN 135BC), Bacillus licheniformis (SAN 136BL) & Saccharomyces boulardii (SAN 158SB) and also specific formulations containing these Probiotic strains

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